So far so good. Quite a bit different than 5. I only played 5 prior to this so it is the only comparison I have.
This religion thing is pissing me off. I hadn't paid attention that there was a religious victory and said "Fuck It!" as Ghandi sends his missionaries to my land and starts converting the non believers. Now I can't even buy a missionary under my own faith to start eradicating his shit from my cities. I have to go wipe that rat bastard out now so I can steal his religion and claim religious victory for myself.
I feel like the game play is a little slower overall than 5 especially in the early years. Wonders take up real estate and seem to take much more production than 5 which will keep civs from hoarding wonders on the harder settings I suspect. The addition of districts is pretty neat since you don't need to have a city on the coast in order to have a harbor. But the districts also take up real estate so you need to make sure you spread out your first couple of cities to allow for enough expansion room.
As far as it being worth buying for $60 right now I don't know if it was worth it. I like the game a lot but I have a hard time justifying $60 for any game. I recently sold a bunch of my old game systems, and some other items, on ebay and made about $900. Bought me a nice new rifle and still had some money left over so I decided to pick it up now instead of waiting.